Effective Treatment for Advanced Breast Cancer Calls for Customized Care
<img class="alignnone size-full wp-image-35147" src="https://mdthinks.com/wp-content/uploads/2017/12/effective-treatment-for-advanced-breast-cancer-calls-for-customized-care.jpg" alt=" Thirty-five-year-old mother of three is surprised to see her cancer in remission thanks to the knowledge of her team of the Mayo Clinic. individualized care. "width =" 805 "height =" 453 "/>
Thirty-five-year-old mother of three is stunned to see her cancer in remission with the knowledge of her Mayo Clinic team and her individualized care.
Amy Conlon arrived at the Mayo Clinic campus in Rochester in August 2016 with little hope. The 35-year-old woman with breast cancer and mother of three has imagined a dark future. She imagined that the future would include a mastectomy and a year of chemotherapy and radiotherapy to combat malignancy stage 4 which to spread to his bones.
"Given the time I had with other health professionals, I thought," Oh my god, this guy gave us all his day, "Amy said. "He was so thorough and gave us so much information, and the best part about all that, is that he really got to know my family and me, and what would be best for my situation to determine my exact treatment plan. most. "
And the treatment plan developed for her by Dr. Goetz, who heads Mayo Clinic's Breast Cancer Research Group and is a member of the Mayo Breast Clinic was nothing like the plan traditional. cross. Instead, she included an ovariectomy to remove her ovaries and two pills: one that lowers estrogen and one that prevents resistance to drugs targeting estrogen.
There was no mastectomy. There was no chemotherapy by infusion, and there was no radiotherapy. And just a year later, there is no cancer.
"At the Mayo Clinic, our most important goal is to provide a personalized treatment plan based on a thorough understanding of the biology of breast cancer, as well as other personal factors that may alter the response to the drug. . said. "We will recommend a treatment designed for you and adapted to your needs."
Innovative and Individualized Care
The discovery that she had metastatic breast cancer was devastating, says Amy, who had an 8-month-old child, a 5-year-old child, and a 9-year-old child at the time of her diagnosis. But Dr. Goetz offered him a different perspective.
"As Dr. Goetz pointed out, people view phase 4 as a death sentence, but anything that happens in stage 4 means that the cancer has spread," says Amy. . "There are several places where it could have spread, and mine went to my bones, if it had gone to my organs, we could have talked about a different thing."
Mayo's breast care team physicians strive to provide their patients with personalized care tailored to their needs.
"We try to match the right patients to the right treatments," says Dr. Goetz. "When patients come to me, my goal is to understand what are the features that allow me to try to individualize therapy for them."
"We try to match good patients with good therapies.When patients come to me, my goal is to understand what are the features that allow me to try to individualize the therapy. for them." – Matthew Goetz, M.D.
The defining feature of Amy's cancer was that it was dependent on estrogen. Drugs that target estrogens, such as tamoxifen and aromatase inhibitors, are considered a standard treatment for estrogen-receptor positive breast cancer. But their benefit is limited and breast cancer cells develop growth mechanisms despite the inhibition of estrogen, Dr. Goetz explains.
This is where interveners inhibit cyclin-dependent 4/6 kinase, or CDK4 / 6. By blocking resistance to estrogen-targeted drugs, these inhibitors result in tumor response rates higher and longer periods of remission.
Another measure against cancer is an injection that Amy receives every three months to harden her bones. It works to prevent bone weakness and fractures, and helps prevent the spread of cancer. After only six months, Amy's cancer declined significantly. Today, she enjoys a complete remission.
Informed and Improved Results
The fact that her cancer is gone is amazing, Amy says. But the success of Amy's treatment, which she will continue to receive until it is no longer effective, is not as surprising for Dr. Goetz.
"We are living a new era in medicine, and in oncology in particular, where the pace of new knowledge and the integration of genomics into our practice have rapidly changed the way we practice. Oncology in 2017 requires a deep understanding of the biology of cancer, "says Dr. Goetz." This deep understanding translates into knowledge that affects the outcome for patients. "
"It's not enough to say," We have what we have here now. "They do better, they constantly think about the next best thing." – Amy Conlon
The insight of her doctors and minimal treatment of the impact have had on Amy's life – she has experienced only a few sparse hair and sores from her mouth – made her trip a painful one. as much more remarkable.
"Their knowledge is absolutely amazing," says Amy. "They went out there to learn the next treatment, heal. It's not enough to say," We have what is here now. "They do better, they constantly think about the next best thing. "
And Mayo providers do all this by developing personal relationships with their patients, Amy adds.
"There are a lot of people going through this place every month," says Amy. "And knowing that they care about you and your family, it's just amazing."